The Histone Methyltransferase Suv39h1 Increases Class Switch Recombination Specifically to IgA
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چکیده
منابع مشابه
The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA.
Ab class (isotype) switching allows the humoral immune system to adaptively respond to different infectious organisms. Isotype switching occurs by intrachromosomal DNA recombination between switch (S) region sequences associated with C(H) region genes. Although isotype-specific transcription of unrearranged (germline) C(H) genes is required for switching, recent results suggest that isotype spe...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2006
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.177.2.1179